The Distribution of Typhoid Vi Agglutinins in Normal Sera with Special Reference to Their Diagnostic Value in Typhoid Fever
نویسنده
چکیده
on the serological diagnosis using the conventional Widal test, the correct interpretation of the results of which is beset with many difficulties. The discovery by Felix and Pitt (1934) of a Vi antigen of B. typhosus, and its serumcounterpart Vi antibody in the sera of typhoid patients and carriers, opened up a new serological approach to the problem of diagnosis of typhoid infection. Bensted (1937) and many other workers since then have confirmed the findings of Felix and his co-workers and acknowledged the importance of Vi agglutinins in the diagnosis of typhoid carriers; but the demonstration of these agglutinins involved a laborious
منابع مشابه
Clinical and Laboratory Findings Including the Diagnostic Value of the Widal Test in Pediatric Cases of Typhoid Fever in Tehran
Background and Objective: The diagnosis of typhoid fever in children is a challenge due to the non-specific clinical picture. The current role of the Widal test for diagnosis in developing countries has not been clear. Materials and Methods: Charts were reviewed on all children ≤ 15 years of age discharg...
متن کاملSignificance and value of the Widal test in the diagnosis of typhoid fever in an endemic area.
The diagnostic value of the Widal test was assessed in an endemic area. The test was done on 300 normal individuals, 297 non-typhoidal fevers and 275 bacteriologically proven cases of typhoid. Of 300 normal individuals, 2% had an H agglutinin titre of 1/160 and 5% had an O agglutinin titre of 1/160. On the basis of these criteria a significant H and/or O agglutinin titre of 1/320 or more was ob...
متن کاملRetrospective audit of the widal test for diagnosis of typhoid Fever in pediatric patients in an endemic region.
INTRODUCTION Although typhoid fever is confirmed by culture of Salmonella Typhi, Widal test is widely used in India but little information exists about its reliability. MATERIALS AND METHODS We examined the performance of Widal test in our hospital for diagnosis of typhoid fever in children. Hundred consecutive pediatric in-patients for whom, the Widal test was requested were grouped into fou...
متن کاملDetection of typhoid carriers by agglutination tests.
Use of the Vi agglutination test in the detection of chronic carriers of Salmonella typhi (S. typhosa) first was suggested by Felix et al. (1935). Since that time study of the test by many workers has resulted in the accumulation of a voluminous literature which has been reviewed by Klein (1943), Felix (1951), Landy and Lamb (1953), and Spaun (1957). Bhatnagar et al. (1938) recommended the use ...
متن کاملInfluence of awareness programs by media in the typhoid fever: a study based on mathematical modeling
In this paper, we propose and analyze a mathematical model describing the effect of awareness programs by public media on the prevalence of Typhoid fever. A threshold quantity $R_{0}$, similar to the basic reproduction number is derived. We investigate the biologically meaningful equilibrium points and their local stability analysis. The global stability analysis has been performed with respect...
متن کامل